CYP4F3 antibody (AA 100-198)

Catalog No. ABIN561693

Product Details anti-CYP4F3 Antibody

Target: CYP4F3 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 3 (CYP4F3))

Binding Specificity: AA 100-198

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: This CYP4F3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse polyclonal antibody raised against a partial recombinant CYP4F3.

Sequence: RIFHPTYIKP VLFAPAAIVP KDKVFYSFLK PWLGDGLLLS AGEKWSRHRR MLTPAFHFNI LKPYMKIFNE SVNIMHAKWQ LLASEGSARL DMFEHISLM

Cross-Reactivity: Human, Mouse

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CYP4F3 (NP_000887, 100 a.a. ~ 198 a.a) partial recombinant protein with GST tag.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 50 % glycerol

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CYP4F3 antibody (ABIN561693)

Uehara, Murayama, Nakanishi, Nakamura, Hashizume, Zeldin, Yamazaki, Uno: "Immunochemical quantification of cynomolgus CYP2J2, CYP4A and CYP4F enzymes in liver and small intestine." in: Xenobiotica; the fate of foreign compounds in biological systems, Vol. 45, Issue 2, pp. 124-30, (2014) (PubMed).

Zhu, Wang, Yang, Guo, Li, Wang, Wang, Huang, Wang, Yang, Ma, Bi: "Comparison of toxicity of benzene metabolite hydroquinone in hematopoietic stem cells derived from murine embryonic yolk sac and adult bone marrow." in: PLoS ONE, Vol. 8, Issue 8, pp. e71153, (2013) (PubMed).

Zhao, He, Bi, Xia, Tao, Li, Ma: "Induction of CYP4F3 by benzene metabolites in human white blood cells in vivo in human promyelocytic leukemic cell lines and ex vivo in human blood neutrophils." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 37, Issue 2, pp. 282-91, (2009) (PubMed).

Target Details for CYP4F3

Target: CYP4F3 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 3 (CYP4F3))

Alternative Name: CYP4F3 (CYP4F3 Products)

Background: Full Gene Name: cytochrome P450, family 4, subfamily F, polypeptide 3
Synonyms: CPF3,CYP4F,LTB4H

Gene ID: 4051

NCBI Accession: NM_000896

Pathways: Steroid Hormone Biosynthesis, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process