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NEDD1 antibody (AA 561-660)

NEDD1 Reactivity: Human IHC (p), ELISA, WB Host: Mouse Monoclonal 7D10 unconjugated
Pubmed (9 references)
Catalog No. ABIN566771
$611.43
Plus shipping costs $45.00
100 μg
Shipping to: United States
Delivery in 11 to 12 Business Days
  • Target See all NEDD1 Antibodies
    NEDD1 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 1 (NEDD1))
    Binding Specificity
    • 15
    • 7
    • 3
    • 2
    • 1
    • 1
    AA 561-660
    Reactivity
    • 32
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 24
    • 7
    • 1
    Mouse
    Clonality
    • 31
    • 1
    Monoclonal
    Conjugate
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEDD1 antibody is un-conjugated
    Application
    • 19
    • 14
    • 13
    • 13
    • 4
    • 3
    • 3
    • 3
    • 2
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
    Purpose
    Mouse monoclonal antibody raised against a partial recombinant NEDD1.
    Sequence
    AGVASSLSEK IADSIGNNRQ NAPLTSIQIR FIQNMIQETL DDFREACHRD IVNLQVEMIK QFHMQLNEMH SLLERYSVNE GLVAEIERLR EENKRLRAHF

    Cross-Reactivity
    Human
    Immunogen
    NEDD1 (NP_690869, 561 a.a. ~ 660 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Clone
    7D10
    Isotype
    IgG2b kappa
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Product Quality tested by: Antibody Reactive Against Recombinant Protein.

    Restrictions
    For Research Use only
  • Buffer
    In 1x PBS, pH 7.4
    Handling Advice
    Aliquot to avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Uehara, Kamasaki, Hiruma, Poser, Yoda, Yajima, Gerlich, Goshima: "Augmin shapes the anaphase spindle for efficient cytokinetic furrow ingression and abscission." in: Molecular biology of the cell, Vol. 27, Issue 5, pp. 812-27, (2016) (PubMed).

    Lecland, Lüders: "The dynamics of microtubule minus ends in the human mitotic spindle." in: Nature cell biology, Vol. 16, Issue 8, pp. 770-8, (2014) (PubMed).

    Stiess, Maghelli, Kapitein, Gomis-Rüth, Wilsch-Bräuninger, Hoogenraad, Toli?-Nørrelykke, Bradke: "Axon extension occurs independently of centrosomal microtubule nucleation." in: Science (New York, N.Y.), Vol. 327, Issue 5966, pp. 704-7, (2010) (PubMed).

    Archinti, Lacasa, Teixidó-Travesa, Lüders: "SPICE--a previously uncharacterized protein required for centriole duplication and mitotic chromosome congression." in: Journal of cell science, Vol. 123, Issue Pt 18, pp. 3039-46, (2010) (PubMed).

    Uehara, Goshima: "Functional central spindle assembly requires de novo microtubule generation in the interchromosomal region during anaphase." in: The Journal of cell biology, Vol. 191, Issue 2, pp. 259-67, (2010) (PubMed).

    Teixidó-Travesa, Villén, Lacasa, Bertran, Archinti, Gygi, Caelles, Roig, Lüders: "The gammaTuRC revisited: a comparative analysis of interphase and mitotic human gammaTuRC redefines the set of core components and identifies the novel subunit GCP8." in: Molecular biology of the cell, Vol. 21, Issue 22, pp. 3963-72, (2010) (PubMed).

    Haren, Stearns, Lüders: "Plk1-dependent recruitment of gamma-tubulin complexes to mitotic centrosomes involves multiple PCM components." in: PLoS ONE, Vol. 4, Issue 6, pp. e5976, (2009) (PubMed).

    Zhu, Fang, Fang: "FAM29A, a target of Plk1 regulation, controls the partitioning of NEDD1 between the mitotic spindle and the centrosomes." in: Journal of cell science, Vol. 122, Issue Pt 15, pp. 2750-9, (2009) (PubMed).

    Zhu, Coppinger, Jang, Yates, Fang: "FAM29A promotes microtubule amplification via recruitment of the NEDD1-gamma-tubulin complex to the mitotic spindle." in: The Journal of cell biology, Vol. 183, Issue 5, pp. 835-48, (2008) (PubMed).

  • Target
    NEDD1 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 1 (NEDD1))
    Alternative Name
    NEDD1 (NEDD1 Products)
    Synonyms
    MGC81767, MGC145237, GCP-WD, TUBGCP7, neural precursor cell expressed, developmentally down-regulated 1 L homeolog, neural precursor cell expressed, developmentally down-regulated 1, cilia and flagella associated protein 54, neural precursor cell expressed, developmentally down-regulated gene 1, nedd1.L, nedd1, CFAP54, NEDD1, Nedd1
    Background
    Full Gene Name: neural precursor cell expressed, developmentally down-regulated 1
    Synonyms: FLJ35902,GCP-WD,TUBGCP7
    Gene ID
    121441
    NCBI Accession
    NP_690869, NM_152905
    Pathways
    M Phase
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