CHRNE antibody (AA 21-239)

Catalog No. ABIN5684150

Product Details anti-CHRNE Antibody

Target: CHRNE (Cholinergic Receptor, Nicotinic, epsilon (Muscle) (CHRNE))

Binding Specificity: AA 21-239

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CHRNE antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purpose: CHRNE Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CHRNE (AA: 21-239) expressed in E. Coli.

Clone: 5F11G8

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CHRNE

Target: CHRNE (Cholinergic Receptor, Nicotinic, epsilon (Muscle) (CHRNE))

Alternative Name: CHRNE (CHRNE Products)

Background:

Description: Acetylcholine receptors at mature mammalian neuromuscular junctions are pentameric protein complexes composed of four subunits in the ratio of two alpha subunits to one beta, one epsilon, and one delta subunit. The acetylcholine receptor changes subunit composition shortly after birth when the epsilon subunit replaces the gamma subunit seen in embryonic receptors. Mutations in the epsilon subunit are associated with congenital myasthenic syndrome.

Aliases: ACHRE, CMS1D, CMS1E, CMS2A, CMS4A, CMS4B, CMS4C, FCCMS, SCCMS

Molecular Weight: 54.7kDa

Gene ID: 1145

HGNC: 3383

UniProt: Q04844