FAM62B antibody (AA 630-760)

Catalog No. ABIN6140463

Product Details anti-FAM62B Antibody

Target: FAM62B (ESYT2) (Extended Synaptotagmin 2 (ESYT2))

Binding Specificity: AA 630-760

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM62B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EKRERPPDHQ HSAQVKRPSV SKEGRKTSIK SHMSGSPGPG GSNTAPSTPV IGGSDKPGME EKAQPPEAGP QGLHDLGRSS SSLLASPGHI SVKEPTPSIA SDISLPIATQ ELRQRLRQLE NGTTLGQSPL G

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 630-760 of human FAM62B (NP_065779.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FAM62B

Target: FAM62B (ESYT2) (Extended Synaptotagmin 2 (ESYT2))

Alternative Name: ESYT2 (ESYT2 Products)

Background: Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding, this occurs most likely via the AP-2 complex. Promotes the localization of SACM1L at endoplasmic reticulum-plasma membrane contact sites (EPCS.,ESYT2,CHR2SYT,E-Syt2,FAM62B,Cell Biology & Developmental Biology,ESYT2

Molecular Weight: 35 kDa/59 kDa/98 kDa/102 kDa/104 kDa

Gene ID: 57488

UniProt: A0FGR8