SMG6 antibody (AA 1160-1419)

Catalog No. ABIN6148132

Product Details anti-SMG6 Antibody

Target: SMG6 (Smg-6 Homolog, Nonsense Mediated mRNA Decay Factor (SMG6))

Binding Specificity: AA 1160-1419

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMG6 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PDTMGKEMGS QEGTRLEDEE EDVVIEDFEE DSEAEGSGGE DDIRELRAKK LALARKIAEQ QRRQEKIQAV LEDHSQMRQM ELEIRPLFLV PDTNGFIDHL ASLARLLESR KYILVVPLIV INELDGLAKG QETDHRAGGY ARVVQEKARK SIEFLEQRFE SRDSCLRALT SRGNELESIA FRSEDITGQL GNNDDLILSC CLHYCKDKAK DFMPASKEEP IRLLREVVLL TDDRNLRVKA LTRNVPVRDI PAFLTWAQVG

Cross-Reactivity: Human, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1160-1419 of human SMG6 (NP_060045.4).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SMG6

Target: SMG6 (Smg-6 Homolog, Nonsense Mediated mRNA Decay Factor (SMG6))

Alternative Name: SMG6 (SMG6 Products)

Background: This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described.,SMG6,C17orf31,EST1A,SMG-6,hSMG5/7a,Cancer,Tumor biomarkers,SMG6

Molecular Weight: 37 kDa/57 kDa/160 kDa

Gene ID: 23293

UniProt: Q86US8