TRPC4 antibody (AA 768-977)

Catalog No. ABIN6149576

Product Details anti-TRPC4 Antibody

Target: TRPC4 (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 (TRPC4))

Binding Specificity: AA 768-977

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPC4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SKESSNSADS DEKSDSEGNS KDKKKNFSLF DLTTLIHPRS AAIASERHNI SNGSALVVQE PPREKQRKVN FVTDIKNFGL FHRRSKQNAA EQNANQIFSV SEEVARQQAA GPLERNIQLE SRGLASRGDL SIPGLSEQCV LVDHRERNTD TLGLQVGKRV CPFKSEKVVV EDTVPIIPKE KHAKEEDSSI DYDLNLPDTV THEDYVTTRL

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 768-977 of human TRPC4 (NP_057263.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TRPC4

Target: TRPC4 (Transient Receptor Potential Cation Channel, Subfamily C, Member 4 (TRPC4))

Alternative Name: TRPC4 (TRPC4 Products)

Background: This gene encodes a member of the canonical subfamily of transient receptor potential cation channels. The encoded protein forms a non-selective calcium-permeable cation channel that is activated by Gq-coupled receptors and tyrosine kinases, and plays a role in multiple processes including endothelial permeability, vasodilation, neurotransmitter release and cell proliferation. Single nucleotide polymorphisms in this gene may be associated with generalized epilepsy with photosensitivity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,TRPC4,HTRP-4,HTRP4,TRP4,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Kinase,Tyrosine kinases,Neuroscience,Calcium Signaling,TRPC4

Molecular Weight: 36 kDa/92 kDa/94 kDa/96 kDa/102 kDa/112 kDa

Gene ID: 7223

UniProt: Q9UBN4