VPS37A antibody (AA 224-397)

Catalog No. ABIN6150132

Product Details anti-VPS37A Antibody

Target: VPS37A (Vacuolar Protein Sorting 37 Homolog A (VPS37A))

Binding Specificity: AA 224-397

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS37A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequence: MPDVPDAFPE LSELSVSQLT DMNEQEEVLL EQFLTLPQLK QIITDKDDLV KSIEELARKN LLLEPSLEAK RQTVLDKYEL LTQMKSTFEK KMQRQHELSE SCSASALQAR LKVAAHEAEE ESDNIAEDFL EGKMEIDDFL SSFMEKRTIC HCRRAKEEKL QQAIAMHSQF HAPL

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 224-397 of human VPS37A (NP_689628.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for VPS37A

Target: VPS37A (Vacuolar Protein Sorting 37 Homolog A (VPS37A))

Alternative Name: VPS37A (VPS37A Products)

Background: This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.,VPS37A,HCRP1,PQBP2,SPG53,Signal Transduction,VPS37A

Molecular Weight: 20 kDa/41 kDa/44 kDa

Gene ID: 137492

UniProt: Q8NEZ2