ZDHHC17 antibody (AA 170-310)

Catalog No. ABIN6150416

Product Details anti-ZDHHC17 Antibody

Target: ZDHHC17 (Zinc Finger, DHHC-Type Containing 17 (ZDHHC17))

Binding Specificity: AA 170-310

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZDHHC17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: TSIVAYLIAK GQDVDMMDQN GMTPLMWAAY RTHSVDPTRL LLTFNVSVNL GDKYHKNTAL HWAVLAGNTT VISLLLEAGA NVDAQNIKGE SALDLAKQRK NVWMINHLQE ARQAKGYDNP SFLRKLKADK EFRQKVMLGT P

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 170-310 of human ZDHHC17 (NP_056151.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for ZDHHC17

Target: ZDHHC17 (Zinc Finger, DHHC-Type Containing 17 (ZDHHC17))

Alternative Name: ZDHHC17 (ZDHHC17 Products)

Background: Palmitoyltransferase that catalyzes the addition of palmitate onto various protein substrates and is involved in a variety of cellular processes. Has no stringent fatty acid selectivity and in addition to palmitate can also transfer onto target proteins myristate from tetradecanoyl-CoA and stearate from octadecanoyl-CoA (By similarity. Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HTT. Also palmitoylates neuronal protein GPM6A as well as SPRED1 and SPRED3. Could also play a role in axonogenesis through the regulation of NTRK1 and the downstream ERK1/ERK2 signaling cascade (By similarity. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. May play a role in Mg(2+ transport. Could also palmitoylate DNAJC5 and regulate its localization to the Golgi membrane (By similarity.,ZDHHC17,HIP14,HIP3,HSPC294,HYPH,Signal Transduction,Neuroscience,ZDHHC17

Molecular Weight: 22 kDa/23 kDa/72 kDa

Gene ID: 23390

UniProt: Q8IUH5