Small Cell Lung Cancer (SCLC) antibody (CF®568)

Catalog No. ABIN6153809

Product Details

Target: Small Cell Lung Cancer (SCLC)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: CF®568

Application: Immunofluorescence (IF), Immunocytochemistry (ICC)

Purpose: Mouse Monoclonal anti-Small Cell Lung Cancer (SCLC) (MOC-52), CF568 Conjugate

Characteristics: This MAb reacts with a membrane-associated protein present in normal and malignant neuroendocrine tissues including small cell lung cancer (SCLC). It stains neural and a variable number of endocrine tissues and in the lung it reacts preferentially with SCLC and carcinoids. Its epitope is destroyed during formalin fixation. This antibody was categorized during the First International Workshop on Small Cell Lung Cancer Antigens held in London in April 1987. There are two major types of Lung Carcinoma: non-small cell, which accounts for 80 % of all cases, and small cell, which accounts for roughly 20 % of all lung cancers reported. The lung continues to be a customary place for cancer migration from tumors elsewhere in the body. Treatment depends on the specific cell type of the cancer, level of progression and status of the individual patient. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Lung Cancer-associated antigen isolated from small cell lung carcinoma-derived cell line

Clone: MOC-52

Isotype: IgG1 kappa

Application Details

Application Notes: Immunocytochemistry frozen 0.5-1.0 μg/mL

• Immunofluorescence 0.5-1 μg/mL
• Optimal dilution for a specific application should be determined by user

Comment:

Human small cell lung carcinoma, adrenal gland

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect from light

Target Details

Target: Small Cell Lung Cancer (SCLC)

Molecular Weight: 145 kDa