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RBP1 antibody (Retinol Binding Protein 1, Cellular) (CF®640R) Primary Antibody

RBP1 Reactivity: Human, Mouse, Rat, Chimpanzee, Goat, Monkey, Rabbit IF, IHC (f) Host: Mouse Monoclonal G4E4 CF®640R
Catalog No. ABIN6172668
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  • Target See all RBP1 Antibodies
    RBP1
    Reactivity
    • 42
    • 30
    • 28
    • 23
    • 22
    • 21
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Chimpanzee, Goat, Monkey, Rabbit
    Host
    • 24
    • 19
    • 7
    Mouse
    Clonality
    • 26
    • 24
    Monoclonal
    Conjugate
    • 28
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This RBP1 antibody is conjugated to CF®640R
    Application
    • 28
    • 24
    • 15
    • 13
    • 13
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Purpose
    Mouse Monoclonal anti-Retinol Binding Protein 1 (G4E4), CF640R Conjugate
    Characteristics
    This MAb recognizes an epitope within the 74-182 C-terminal sequence (11kD peptide fragment) of human serum Cellular Retinol Binding Protein 1 (CRBP 1), a single-chain glycoprotein belonging to the superfamily of hydrophobic molecule transporter proteins, which is responsible for transport of retinol (vitamin A1) from the liver to peripheral target tissues, like the eye, where it mediates the cellular uptake. CRBP 1 is synthesized by hepatic parenchymal cells where it becomes bound to its ligand retinol and is then released into the circulation, where it binds further to the protein transthyretin, to form a transporting complex, which is big enough not to be lost by filtration through the kidney glomeruli. It is detected in nearly all tissues with higher expression in adult ovary, pancreas, pituitary gland, adrenal gland, and fetal liver. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    Immunogen
    Retinol binding protein-1 purified from human plasma
    Clone
    G4E4
    Isotype
    IgG1 kappa
  • Application Notes
    Immunohistology formalin-fixed 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Immunofluorescence 1-2 μg/mL
    • Optimal dilution for a specific application should be determined by user
    Comment

    Hepatic or ovarian carcinoma

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    100 μg/mL
    Buffer
    PBS/0.1 % BSA/0.05 % azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from light
  • Target
    RBP1
    Alternative Name
    Retinol Binding Protein 1 (RBP1 Products)
    Synonyms
    RBBP-1, RBBP1, RBP-1, RBP1, CRABP-I, CRBP, CRBP1, CRBPI, RBPC, cb465, rbp1, wu:fb75e07, zgc:73335, CRABP1, Crbp, Rbp-1, AT-rich interaction domain 4A, retinol binding protein 1, retinol binding protein 1a, cellular, retinol binding protein 1 L homeolog, retinol binding protein 1, cellular, ARID4A, RBP1, rbp5, rbp1.L, rbp1, Rbp1
    Molecular Weight
    21-25 kDa
    Gene ID
    5947, 5948, 5950
    UniProt
    P02753
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