CLEC16A antibody (C-Term)

Catalog No. ABIN6242841

Product Details anti-CLEC16A Antibody

Target: CLEC16A (C-Type Lectin Domain Family 16, Member A (CLEC16A))

Binding Specificity: AA 773-805, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLEC16A antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CLEC16A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 773-805 amino acids from the C-terminal region of human CLEC16A.

Clone: RB51799

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

Target Details for CLEC16A

Target: CLEC16A (C-Type Lectin Domain Family 16, Member A (CLEC16A))

Alternative Name: CLEC16A (CLEC16A Products)

Background: Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PARK2 pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PARK2 pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteosomal degradation, RNF41/NRDP1 which regulates proteosomal degradation of PARK2. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health.

Molecular Weight: 117715

UniProt: Q2KHT3