YWHAZ antibody (Tyrosine 3-Monooxygenase/tryptophan 5-Monooxygenase Activation Protein, zeta Polypeptide) (pSer58)

Catalog No. ABIN6256377

Product Details anti-YWHAZ Antibody

Target:

YWHAZ

Binding Specificity: pSer58

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YWHAZ antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)

Specificity: Phospho-14-3-3 zeta (Ser58) Antibody detects endogenous levels of 14-3-3 zeta only when phosphorylated at Serine 58

Cross-Reactivity: Human, Mouse (Murine), Rat (Rattus)

Purification: The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Immunogen: A synthesized peptide derived from human 14-3-3 zeta around the phosphorylation site of Serine 58

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details for YWHAZ

Target:

YWHAZ

Alternative Name: 14-3-3 zeta (YWHAZ Antibody Abstract)

Synonyms: 14-3-3-zeta, KCIP-1, YWHAD, 14-3-3zeta, Ywhaz, ACYPI003154, 14-3-3z, kcip-1, ywhaq, 1433z, ywhaz, ywhazb, 1110013I11Rik, AI596267, AL022924, AU020854, ywhaza, fb14h09, wu:fb05g08, wu:fb14h09, ywhai, zgc:55807, 14-3-3, 14-3-3 zeta, 14-3-3ZETA, 14-3-3leo, 2G1, 4-3-3 zeta, 5.11, 549, BEST:GH05075, CG17870, D14-3-3, D14-3-3zeta, Dmel\\CG17870, K, LEO, Leo, PAR-5, PAR5, Par-5, d14-3-3zeta, l(2)07103, l(2)46CFe, l(2)46Ee, leo, par-5, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta, 14-3-3 protein zeta, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta L homeolog, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta S homeolog, 14-3-3 protein zeta/delta pseudogene, CG17870 gene product from transcript CG17870-RE, YWHAZ, 14-3-3zeta, ywhaz, 1433z, ywhaz.L, Ywhaz, ywhaz.S, LOC100855903

Background:

Description: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.

Gene: YWHAZ

Molecular Weight: 28kDa

Gene ID: 7534

UniProt: P63104

Pathways: Apoptosis, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location