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14-3-3 zeta Products

(14-3-3 zeta (YWHAZ))

Categories

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008].

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Featured 14-3-3 zeta Categories

14-3-3 zeta Antibodies

High quality antibodies with extensive validation data.

14-3-3 zeta ELISA Kits

Reliable ELISA kits for a wide range of species.

14-3-3 zeta Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended 14-3-3 zeta Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF, FACS
Validations
  • (8)
Cat. No. ABIN7142109
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (5)
Cat. No. ABIN7142105
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (5)
Cat. No. ABIN6256377
Quantity 100 μL
Datasheet Datasheet

Recommended 14-3-3 zeta ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6974054
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6971018
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6960600
Quantity 96 tests
Datasheet Datasheet

Recommended 14-3-3 zeta Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325557
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1325555
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3120842
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our 14-3-3 zeta products

Ihle, Trautmann, Kuenstlinger, Huss, Heydt, Fassunke, Wardelmann, Bauer, Schildhaus, Buettner, Merkelbach-Bruse: "miRNA-221 and miRNA-222 induce apoptosis via the KIT/AKT signalling pathway in gastrointestinal stromal tumours." in: Molecular oncology, Vol. 9, Issue 7, pp. 1421-33, (2016) (PubMed).

Joshi, Su, Chandramouli, Khoo, Jeong, Young, Lessey, Fazleabas: "Altered expression of microRNA-451 in eutopic endometrium of baboons (Papio anubis) with endometriosis." in: Human reproduction (Oxford, England), Vol. 30, Issue 12, pp. 2881-91, (2015) (PubMed).

Hatzipetros, Gocze, Koszegi, Jaray, Szereday, Polgar, Farkas, Farkas: "Investigating the clinical potential for 14-3-3 zeta protein to serve as a biomarker for epithelial ovarian cancer." in: Journal of ovarian research, Vol. 6, Issue 1, pp. 79, (2014) (PubMed).

Nagappan, Park, Park, Hong, Yumnam, Lee, Kim, Kim, Lee, Lee, Cho, Lee, Won, Cho, Kim: "Helicobacter pylori infection combined with DENA revealed altered expression of p53 and 14-3-3 isoforms in Gulo-/- mice." in: Chemico-biological interactions, Vol. 206, Issue 2, pp. 143-52, (2013) (PubMed).

Wang, Nesland, Suo, Trope, Holm: "The prognostic value of 14-3-3 isoforms in vulvar squamous cell carcinoma cases: 14-3-3? and ? are independent prognostic factors for these tumors." in: PLoS ONE, Vol. 6, Issue 9, pp. e24843, (2011) (PubMed).

Li, Zhao, Du, Park, Sun, Bernal-Mizrachi, Aitken, Khuri, Fu: "Down-regulation of 14-3-3zeta suppresses anchorage-independent growth of lung cancer cells through anoikis activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 1, pp. 162-7, (2008) (PubMed).

Mateo, Llorca, Infante, Rodríguez-Rodríguez, Berciano, Combarros: "Gene-gene interaction between 14-3-3 zeta and butyrylcholinesterase modulates Alzheimer's disease risk." in: European journal of neurology : the official journal of the European Federation of Neurological Societies, Vol. 15, Issue 3, pp. 219-22, (2008) (PubMed).

Li, Mofunanya, Harris, Takemaru: "Chibby cooperates with 14-3-3 to regulate beta-catenin subcellular distribution and signaling activity." in: The Journal of cell biology, Vol. 181, Issue 7, pp. 1141-54, (2008) (PubMed).

Aitken: "14-3-3 proteins: a historic overview." in: Seminars in cancer biology, Vol. 16, Issue 3, pp. 162-72, (2006) (PubMed).

Gu, Jin, Choi, Baek, Yeo, Lee: "Protein kinase A phosphorylates and regulates dimerization of 14-3-3 epsilon." in: FEBS letters, Vol. 580, Issue 1, pp. 305-10, (2006) (PubMed).

Synonyms and alternative names related to 14-3-3 zeta

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta (YWHAZ), 14-3-3 protein zeta (14-3-3zeta), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta (ywhaz), 14-3-3 protein zeta (1433z), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta L homeolog (ywhaz.L), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Ywhaz), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta (Ywhaz), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta S homeolog (ywhaz.S), 14-3-3 protein zeta/delta pseudogene (LOC100855903), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (ywhaz), CG17870 gene product from transcript CG17870-RE (14-3-3zeta), tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta (Ywhaz), 2G1, 4-3-3 zeta, 5.11, 14-3-3, 14-3-3 zeta, 14-3-3-zeta, 14-3-3leo, 14-3-3z, 14-3-3zeta, 14-3-3ZETA, 549, 1433z, 1110013I11Rik, ACYPI003154, AI596267, AL022924, AU020854, BEST:GH05075, CG17870, D14-3-3, D14-3-3zeta, d14-3-3zeta, Dmel\\CG17870, fb14h09, K, KCIP-1, kcip-1, l(2)07103, l(2)46CFe, l(2)46Ee, LEO, Leo, leo, PAR-5, Par-5, par-5, PAR5, wu:fb05g08, wu:fb14h09, YWHAD, ywhai, ywhaq, Ywhaz, ywhaz, ywhaza, ywhazb, zgc:55807

Protein level used designations for 14-3-3 zeta

  • 14-3-3 delta
  • 14-3-3 protein zeta/delta
  • 14-3-3 protein/cytosolic phospholipase A2
  • 14-3-3 zeta
  • phospholipase A2
  • protein kinase C inhibitor protein 1
  • protein kinase C inhibitor protein-1
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, delta polypeptide
  • tyrosine 3/tryptophan 5 -monooxygenase activation protein, zeta polypeptide
  • 14-3-3zeta
  • 14-3-3 protein zeta
  • tyrosine 3-monooxygenase protein zeta polypeptide
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide b
  • FAS
  • KCIP-1
  • factor activating exoenzyme S
  • SEZ-2
  • mitochondrial import stimulation factor S1 subunit
  • 14-3-3 protein zeta a
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide a
  • tyrosine 3/tryptophan 5-monooxygenase activation protein zeta polypeptide
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide
  • 14-3-3zeta-PA
  • 14-3-3zeta-PB
  • 14-3-3zeta-PC
  • 14-3-3zeta-PD
  • 14-3-3zeta-PE
  • 14-3-3zeta-PF
  • 14-3-3zeta-PG
  • 14-3-3zeta-PH
  • 14-3-3zeta-PI
  • 14-3-3zeta-PJ
  • 14-3-3zeta-PK
  • 14-3-3zeta-PL
  • CG17870-PA
  • CG17870-PB
  • CG17870-PC
  • CG17870-PD
  • CG17870-PE
  • CG17870-PF
  • CG17870-PG
  • CG17870-PH
  • CG17870-PI
  • CG17870-PJ
  • CG17870-PK
  • CG17870-PL
  • D14 3 3 protein
  • Leonardo-13-3-3
  • complementation group K
  • leonardo
  • leonardo 14-3-3
  • tyrosine 3-monooxygenase
  • tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
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