IL17RA antibody (Interleukin 17 Receptor A)

Details for Product anti-IL17RA Antibody No. ABIN6257288
Antigen
Reactivity
Human, Mouse (Murine)
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66
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Host
Rabbit
92
17
10
6
Clonality
Polyclonal
Conjugate
This IL17RA antibody is un-conjugated
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10
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2
2
2
2
2
1
1
1
1
1
1
1
1
1
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1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
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64
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5
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4
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Options
Immunogen A synthesized peptide
Isotype IgG
Specificity IL17RA Antibody detects endogenous levels of total IL17RA
Cross-Reactivity Human, Mouse (Murine)
Purification The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
Antigen
Alternative Name IL17RA (IL17RA Antibody Abstract)
Background

Description: Receptor for IL17A (PubMed:17911633, PubMed:9367539). Receptor for IL17F (PubMed:19838198, PubMed:17911633). Binds to IL17A with higher affinity than to IL17F (PubMed:17911633). Binds IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RC (PubMed:16785495). Also binds heterodimers formed by IL17A and IL17F as part of a heterodimeric complex with IL17RC (PubMed:18684971). Receptor for IL17C as part of a heterodimeric complex with IL17RE (PubMed:21993848). Activation of IL17RA leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1, CXCL8/IL8 and IL6 (PubMed:16785495, PubMed:17911633, PubMed:18684971).

Gene: IL17RA

Molecular Weight 90 kDa
Gene ID 23765
UniProt Q96F46
Pathways SARS-CoV-2 Protein Interactome
Application Notes WB 1:500~1:1000, IF/ICC 1:100-1:500
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months
Supplier Images
Image no. 1 for anti-Interleukin 17 Receptor A (IL17RA) antibody (ABIN6257288) ABIN6274673 staining LOVO by IF/ICC. The sample were fixed with PFA and permeabilized...
Image no. 2 for anti-Interleukin 17 Receptor A (IL17RA) antibody (ABIN6257288) Western blot analysis of extracts from LOVO cells, using IL17RAantibody.The lane on t...