Cytochrome P450 2A6/7/13 antibody

Catalog No. ABIN6261195

Product Details

Target: Cytochrome P450 2A6/7/13

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Application: ELISA, Western Blotting (WB)

Specificity: Cytochrome P450 2A6/7/13 Antibody detects endogenous levels of total Cytochrome P450 2A6/7/13

Cross-Reactivity: Human

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human Cytochrome P450 2A6/7/13

Isotype: IgG

Application Details

Application Notes: WB 1:1000-3000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C.Stable for 12 months from date of receipt

Expiry Date: 12 months

Target Details

Target: Cytochrome P450 2A6/7/13

Background:

Description: Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4-cineole 2-exo-monooxygenase. Possesses low phenacetin O-deethylation activity.

Gene: CYP2A6

Molecular Weight: 56 kDa

Gene ID: 1548

UniProt: P11509, P20853, Q16696