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Integrin beta 4 antibody (C-Term)

ITGB4 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6262617
  • Target See all Integrin beta 4 (ITGB4) Antibodies
    Integrin beta 4 (ITGB4)
    Binding Specificity
    • 16
    • 10
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 80
    • 25
    • 24
    • 3
    • 3
    Human, Mouse, Rat
    Host
    • 55
    • 36
    • 7
    • 2
    Rabbit
    Clonality
    • 51
    • 49
    Polyclonal
    Conjugate
    • 52
    • 8
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Integrin beta 4 antibody is un-conjugated
    Application
    • 50
    • 42
    • 30
    • 27
    • 18
    • 14
    • 14
    • 13
    • 13
    • 9
    • 7
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    Integrin beta 4 Antibody detects endogenous levels of total Integrin beta 4.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Chicken
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human Integrin beta 4, corresponding to a region within C-terminal amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product ITGB4 Primary Antibody
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Target
    Integrin beta 4 (ITGB4)
    Alternative Name
    ITGB4 (ITGB4 Products)
    Synonyms
    AA407042 antibody, C230078O20 antibody, CD104 antibody, integrin subunit beta 4 antibody, integrin beta 4 antibody, ITGB4 antibody, Itgb4 antibody
    Background

    Description: Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464).

    Gene: ITGB4

    Molecular Weight
    202 kDa
    Gene ID
    3691
    UniProt
    P16144
    Pathways
    Integrin Complex
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