P2RX7 antibody (C-Term)
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- Target See all P2RX7 Antibodies
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This P2RX7 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Specificity
- P2X7 Antibody detects endogenous levels of total P2X7.
- Purification
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human P2X7, corresponding to a region within C-terminal amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product P2RX7 Primary Antibody
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anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 226-452) antibody
P2RX7 Reactivity: Human WB, IHC, ELISA, FACS Host: Mouse Monoclonal 7G1D6 unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (Center) antibodyP2RX7 Reactivity: Human, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 563-592) antibodyP2RX7 Reactivity: Human, Mouse WB, IHC (p) Host: Rabbit Polyclonal RB21714 unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (N-Term) antibodyP2RX7 Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Guinea Pig WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 136-152), (Extracellular Loop) antibodyP2RX7 Reactivity: Human, Mouse, Rat WB, IHC, FACS, IF, ICC, LCI Host: Rabbit Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 136-152), (Extracellular Loop) antibody (FITC)P2RX7 Reactivity: Human, Mouse, Rat FACS, IF, ICC, LCI Host: Rabbit Polyclonal FITC
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 47-334) antibodyP2RX7 Reactivity: Human WB, IHC, ICC, IP Host: Rabbit Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (N-Term) antibodyVerified P2RX7 Reactivity: Human, Mouse WB, IHC, ELISA, IF Host: Goat Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (Internal Region) antibodyP2RX7 Reactivity: Human, Monkey IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (N-Term) antibodyP2RX7 Reactivity: Human, Mouse WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C. Stable for 12 months from date of receipt.
- Expiry Date
- 12 months
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- Target
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
- Alternative Name
- P2RX7 (P2RX7 Products)
- Background
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Description: Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells (PubMed:21821797, PubMed:23303206).
Gene: P2RX7
- Molecular Weight
- 69 kDa
- Gene ID
- 5027
- UniProt
- Q99572
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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