SETD2 antibody (SET Domain Containing 2)

Details for Product anti-SETD2 Antibody No. ABIN6290482
Antigen
Reactivity
Mouse (Murine), Rat (Rattus)
76
18
15
3
2
2
Host
Rabbit
62
9
7
Clonality
Polyclonal
Conjugate
This SETD2 antibody is un-conjugated
6
4
4
4
4
4
2
2
2
2
2
2
Application
Western Blotting (WB)
41
39
38
16
6
4
3
2
1
1
Options
Immunogen Recombinant protein of human SETD2
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name SETD2 (SETD2 Antibody Abstract)
Background Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
Molecular Weight 287.597 kDa
Gene ID 29072
UniProt Q9BYW2
Pathways Tube Formation
Application Notes WB 1:200 - 1:500
Comment

Ubiquitously expressed

Restrictions For Research Use only
Buffer PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-SET Domain Containing 2 (SETD2) antibody (ABIN6290482) Western blot analysis of extracts of various cell lines, using SETD2 antibody (ABIN62...