Nhs antibody

Catalog No. ABIN6293547

Product Details anti-Nhs Antibody

Target: Nhs (Nance-Horan Syndrome (Congenital Cataracts and Dental Anomalies) (Nhs))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nhs antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human NHS

Isotype: IgG

Application Details

Application Notes: WB 1:200 - 1:2000

Comment:

Detected at low levels in all tissues analyzed, Detected in fetal and adult brain, lens, retina, retinal pigment epithelium, placenta, lymphocytes and fibroblasts, Levels in retinal pigment epithelium, placenta, lymphocytes, and fibroblasts are very low, Expressed also in kidney, lung and thymus

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20C. Avoid freeze / thaw cycles.

Target Details for Nhs

Target: Nhs (Nance-Horan Syndrome (Congenital Cataracts and Dental Anomalies) (Nhs))

Alternative Name: NHS (Nhs Products)

Synonyms: CTRCT40 antibody, CXN antibody, SCML1 antibody, NHS actin remodeling regulator antibody, NHS antibody

Background: This gene encodes a protein containing four conserved nuclear localization signals. The encoded protein functions in eye, tooth, craniofacial and brain development, and it can regulate actin remodeling and cell morphology. Mutations in this gene have been shown to cause Nance-Horan syndrome, and also X-linked cataract-40. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 179.135 kDa

Gene ID: 4810

UniProt: Q6T4R5