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Keratin 10 antibody

KRT10 Reactivity: Human, Mouse IHC Host: Mouse Monoclonal unconjugated
Catalog No. ABIN6297641
  • Target See all Keratin 10 (KRT10) Antibodies
    Keratin 10 (KRT10)
    Reactivity
    • 114
    • 56
    • 49
    • 27
    • 18
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 71
    • 47
    • 1
    Mouse
    Clonality
    • 62
    • 57
    Monoclonal
    Conjugate
    • 65
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Keratin 10 antibody is un-conjugated
    Application
    • 75
    • 55
    • 51
    • 36
    • 34
    • 22
    • 14
    • 13
    • 12
    • 11
    • 10
    • 8
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC)
    Purpose
    Mouse anti-Human/Mouse Cytokeratin 10 Antibody [IHC only]
    Specificity
    Cytoplasmic
    Purification
    Skin extract from a human psoriasis patient was used as the immunogen for this Cytokeratin 10 antibody.
    Immunogen
    Skin extract from a human psoriasis patient was used as the immunogen for this Cytokeratin 10 antibody.
    Top Product
    Discover our top product KRT10 Primary Antibody
  • Application Notes
    Prediluted format : incubate for 30 min at RT (2)
    Restrictions
    For Research Use only
  • Buffer
    Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target
    Keratin 10 (KRT10)
    Alternative Name
    Keratin, type I cytoskeletal 10 (KRT10 Products)
    Synonyms
    BCIE antibody, BIE antibody, CK10 antibody, EHK antibody, K10 antibody, KPP antibody, D130054E02Rik antibody, K1C1 antibody, Krt-1.10 antibody, Krt1-10 antibody, Ka10 antibody, Ker10 antibody, KRT10 antibody, KRT25 antibody, KRT27 antibody, KRT28 antibody, keratin 10 antibody, keratin 10, type I S homeolog antibody, keratin, type I cytoskeletal 25 antibody, KRT10 antibody, Krt10 antibody, krt10.S antibody, LOC101085587 antibody
    Background

    Target Description: This antibody recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). cytokeratin 10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of cytokeratin 10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, cytokeratin 10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), cytokeratin 10 is detected very frequently. Expression of cytokeratin 10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

    Gene Symbol: KRT10///KPP

    Gene ID
    3858
    UniProt
    P13645
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