CD37 antibody
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- Target See all CD37 (TSPAN26) Antibodies
- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CD37 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
- Purpose
- Mouse anti-Human CD37 Antibody [Sodium Azide Free]
- Specificity
- Cell surface
- Purification
- Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the CD37 antibody.
- Immunogen
- Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the CD37 antibody.
- Top Product
- Discover our top product TSPAN26 Primary Antibody
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- Application Notes
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Functional Activity (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL - Restrictions
- For Research Use only
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- Buffer
- In 1X PBS, BSA free, sodium azide free
- Preservative
- Azide free
- Storage
- 4 °C,-20 °C
- Storage Comment
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Target
- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
- Alternative Name
- Leukocyte antigen CD37 (TSPAN26 Products)
- Synonyms
- Tspan26 antibody, GP52-40 antibody, TSPAN26 antibody, CD37 antigen antibody, CD37 molecule antibody, Cd37 antibody, CD37 antibody
- Background
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Target Description: Recognizes a protein of 33-55 kDa, identified as CD37 (Workshop V, Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL).
Gene Symbol: CD37///TSPAN26
- Gene ID
- 951
- UniProt
- P11049
- Pathways
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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