Tetraspanin 26 (TSPAN26) antibody

Details for Product No. ABIN6297658
Antigen
  • Tspan26
  • GP52-40
  • TSPAN26
  • CD37 antigen
  • CD37 molecule
  • Cd37
  • CD37
Reactivity
Human
143
15
5
2
2
1
1
1
Host
Mouse
100
46
Clonality
Monoclonal
Conjugate
Un-conjugated
13
12
10
6
5
4
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Functional Studies (Func), Immunofluorescence (IF)
93
56
56
38
27
14
13
9
6
5
5
4
2
2
1
Options
Purpose Mouse anti-Human CD37 Antibody [Sodium Azide Free]
Immunogen Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the CD37 antibody.
Specificity Cell surface
Purification Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the CD37 antibody.
Antigen
Alternative Name Leukocyte antigen CD37 (TSPAN26 Antibody Abstract)
Background

Target Description: Recognizes a protein of 33-55 kDa, identified as CD37 (Workshop V, Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL).

Gene Symbol: CD37///TSPAN26

Gene ID 951
UniProt P11049
Pathways Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Application Notes Functional Activity (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Restrictions For Research Use only
Buffer In 1X PBS, BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
Did you look for something else?