CD31 antibody (Platelet/endothelial Cell Adhesion Molecule) (PE)

Details for Product anti-PECAM1 Antibody No. ABIN6297663
Antigen
  • CD31
  • CD31/EndoCAM
  • GPIIA'
  • PECA1
  • PECAM-1
  • endoCAM
  • C85791
  • Cd31
  • Pecam
  • platelet/endothelial cell adhesion molecule 1
  • platelet and endothelial cell adhesion molecule 1
  • pecam1
  • PECAM1
  • Pecam1
Reactivity
Human
956
265
139
127
125
33
22
18
12
12
9
9
8
3
3
3
3
3
1
1
1
1
1
Host
Mouse
740
315
110
9
5
1
1
1
Clonality
Monoclonal
Conjugate
This CD31 antibody is conjugated to PE
89
87
81
46
20
16
16
15
14
10
10
10
10
9
9
9
9
9
9
9
9
9
9
9
9
9
6
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)
747
506
402
366
162
147
127
103
59
33
20
20
15
15
13
11
10
8
3
2
1
1
1
1
1
1
Options
Purpose Mouse anti-Human PECAM-1 Antibody [Sodium Azide Free]
Immunogen Stimulated human leukocytes (Workshop VI) were used as the immunogen for the PECAM-1 antibody.
Specificity Cell surface and cytoplasm of endothelial cells
Purification Stimulated human leukocytes (Workshop VI) were used as the immunogen for the PECAM-1 antibody.
Plasmids, Primers & others Plasmids, Primers & others CD31 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Platelet endothelial cell adhesion molecule (PECAM1 Antibody Abstract)
Background

Target Description: CD31 (PECAM-1) is a transmembrane glycoprotein member of the immunoglobulin supergene family of adhesion molecules. CD31 is expressed by stem cells of the hematopoietic system and is primarily used to identify and concentrate these cells for experimental studies as well as for bone marrow transplantation. Anti-CD31 has shown to be highly specific and sensitive for vascular endothelial cells. Staining of nonvascular tumors (excluding hematopoietic neoplasms) is rare. CD31 mAb reacts with normal, benign, and malignant endothelial cells which make up blood vessel lining. The level of CD31 expression can help to determine the degree of tumor angiogenesis, and a high level of CD31 expression may imply a rapidly growing tumor and potentially a predictor of tumor recurrence.

Gene Symbol: PECAM1

Gene ID 5175
UniProt P16284
Pathways Regulation of Actin Filament Polymerization
Application Notes Western blot: 2-4 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Restrictions For Research Use only
Buffer In 1X PBS, BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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