CD3E antibody (CD3e Molecule, epsilon (CD3-TCR Complex))

Details for Product anti-CD3E Antibody No. ABIN6297680
Antigen
  • cd3e
  • CD3E
  • t3e
  • tcre
  • AI504783
  • CD3
  • CD3epsilon
  • T3e
  • T3E
  • TCRE
  • CD3e molecule
  • CD3 antigen, epsilon polypeptide
  • cd3e
  • CD3E
  • Cd3e
Reactivity
Human, Monkey
434
360
83
73
31
11
11
11
10
8
6
6
5
5
4
4
4
4
4
2
1
Host
Mouse
287
235
151
55
42
10
2
1
Clonality
Monoclonal
Conjugate
This CD3E antibody is un-conjugated
72
64
60
43
17
17
15
10
8
8
8
7
7
7
6
6
5
5
5
5
5
5
5
5
5
5
5
5
5
5
4
4
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
Application
Activation (Act), Flow Cytometry (FACS), Functional Studies (Func), Immunofluorescence (IF), Proliferation Assay (ProA)
554
288
238
168
166
121
60
43
34
34
23
22
16
14
12
12
4
3
2
1
1
1
Options
Purpose Mouse anti-Human/Monkey CD3e Antibody [Sodium Azide Free]
Immunogen Stimulated human leukocytes were used as the immunogen for the CD3e antibody.
Specificity Cell surface and cytoplasmic
Purification Stimulated human leukocytes were used as the immunogen for the CD3e antibody.
Plasmids, Primers & others Plasmids, Primers & others CD3E products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name T-cell surface glycoprotein CD3 epsilon chain (CD3E Antibody Abstract)
Background

Target Description: Recognizes the epsilon-chain of CD3 (Workshop V, Code: CD03.09), which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28 kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.

Gene Symbol: CD3E///T3E
Gene ID 916
UniProt P07766
Pathways TCR Signaling, CXCR4-mediated Signaling Events
Application Notes Functional Activity: Induce T cell activation and proliferation (Order SAF formulation)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Restrictions For Research Use only
Buffer In 1X PBS, BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.