ITGAL antibody (Integrin alpha-L)

Details for Product anti-ITGAL Antibody No. ABIN6297695
Antigen
  • CD11A
  • LFA-1
  • LFA1A
  • (p180)
  • Cd11a
  • LFA-1A
  • Ly-15
  • Ly-21
  • CD11a
  • ITGAL
  • integrin subunit alpha L
  • integrin alpha L
  • ITGAL
  • Itgal
Reactivity
Human
395
164
40
13
11
10
10
9
8
6
1
1
Host
Mouse
363
117
91
7
2
1
Clonality
Monoclonal
Conjugate
This ITGAL antibody is un-conjugated
78
62
55
21
11
10
8
6
6
5
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Flow Cytometry (FACS), Functional Studies (Func), Immunofluorescence (IF)
460
139
113
105
76
69
58
49
15
13
11
9
8
8
3
2
1
1
1
1
1
1
Options
Purpose Mouse anti-Human CD11a Antibody [Sodium Azide Free]
Immunogen Stimulated human leukocytes were used as the immunogen for this CD11b antibody.
Specificity Cell surface
Purification Stimulated human leukocytes were used as the immunogen for this CD11b antibody.
Plasmids, Primers & others Plasmids, Primers & others ITGAL products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Integrin alpha-L (ITGAL Antibody Abstract)
Background

Target Description: This antibody recognizes a protein of 180 kDa, identified as CD11a. CD11a complexes with the beta 2 subunit of the integrin family, CD18, to form the cell surface heterodimer called LFA-1 or CD11a/CD18. LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses.

Gene Symbol: ITGAL///CD11A

Gene ID 3683
UniProt P20701
Pathways Activated T Cell Proliferation, Integrin Complex
Application Notes Functional Testing: order BSA/azide-free format
FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
Restrictions For Research Use only
Buffer In 1X PBS ( pH 7.4), BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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