CD63 antibody (CD63 Molecule)

Details for Product anti-CD63 Antibody No. ABIN6297771
Antigen
  • C75951
  • ME491
  • Tspan30
  • LAMP-3
  • MLA1
  • OMA81H
  • TSPAN30
  • TSP29FA
  • CD63 antigen
  • CD63 molecule
  • Cd63 molecule
  • Cd63
  • CD63
Reactivity
Human
410
124
24
5
4
4
3
3
3
3
3
3
3
3
3
3
2
1
Host
Mouse
324
112
4
4
Clonality
Monoclonal
Conjugate
This CD63 antibody is un-conjugated
34
33
25
22
11
9
6
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
1
Application
Immunohistochemistry (IHC)
286
192
132
125
85
80
66
66
52
27
22
14
7
7
4
2
1
Options
Purpose Mouse anti-Human CD63 Antibody Cocktail [IHC only]
Immunogen The smooth plasma membrane fraction of MeWo cells (NKI/C3) and recombinant human full-length protein (LAMP3/968) were used as the immunogen for the CD63 antibody cocktail.
Specificity Cytoplasmic
Purification The smooth plasma membrane fraction of MeWo cells (NKI/C3) and recombinant human full-length protein (LAMP3/968) were used as the immunogen for the CD63 antibody cocktail.
Plasmids, Primers & others Plasmids, Primers & others CD63 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CD63 antigen (CD63 Antibody Abstract)
Background

Target Description: This mAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Gene Symbol: CD63///MLA1///TSPAN30

Gene ID 967
UniProt P08962
Application Notes Prediluted format : incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.