CD63 antibody (CD63 Molecule)

Details for Product anti-CD63 Antibody No. ABIN6297776
Antigen
  • C75951
  • ME491
  • Tspan30
  • LAMP-3
  • MLA1
  • OMA81H
  • TSPAN30
  • TSP29FA
  • CD63 antigen
  • CD63 molecule
  • Cd63 molecule
  • Cd63
  • CD63
Reactivity
Human, Mouse (Murine)
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1
Host
Mouse
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4
Clonality
Monoclonal
Conjugate
This CD63 antibody is un-conjugated
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25
22
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6
3
3
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3
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1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
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Options
Purpose Mouse anti-Human/Mouse CD63 Antibody [Sodium Azide Free]
Immunogen The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this CD63 antibody.
Specificity Cytoplasmic
Purification The smooth plasma membrane fraction of MeWo cells was used as the immunogen for this CD63 antibody.
Plasmids, Primers & others Plasmids, Primers & others CD63 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name CD63 antigen (CD63 Antibody Abstract)
Background

Target Description: The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. It is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. Deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

Gene Symbol: CD63///MLA1///TSPAN30

Gene ID 967
UniProt P08962
Application Notes FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
WB: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer In 1X PBS ( pH 7.4), BSA free, sodium azide free
Preservative Azide free
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.