PGC antibody (Pepsinogen C) (Biotin)

Details for Product anti-PGC Antibody No. ABIN6297820
Antigen
  • PEPC
  • PGII
  • 2210410L06Rik
  • Upg-1
  • Upg1
  • CPGC
  • gastricsin
  • PG1
  • Pg-1
  • PGNC
  • PGC
  • Gastricsin
  • progastricsin (pepsinogen C)
  • progastricsin
  • PGC
  • Pgc
Reactivity
Human
129
48
37
12
2
2
1
Host
Mouse
118
46
2
Clonality (Clone)
Monoclonal ()
Conjugate
This PGC antibody is conjugated to Biotin
23
11
6
4
4
4
4
4
4
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
122
70
49
18
13
10
9
8
4
3
3
2
1
Options
Purpose Mouse anti-Human PGC Biotinylated Antibody
Immunogen This antibody was produced by fusion of mouse myeloma with B cells obtained from a mouse immunized with a recombinant protein immunogen. The IgG fraction of tissue culture supernatant was purified by Protein G/A affinity chromatography.
Clone 4A3-G4-G6
Isotype IgG1
Plasmids, Primers & others Plasmids, Primers & others PGC products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name PGC (PGC Antibody Abstract)
Background

Target Description: PGC gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.

UniProt P20142
Application Notes ELISA (recommended dilution= 1:320,000), Western Blotting (recommended dilution= 1:1,000-5,000)
Restrictions For Research Use only
Reconstitution A separate vial of dilution buffer is provided for reconstitution. The antibody is supplied lyophilized, originally containing PBS, without preservative stabilizers (e. g. sodium azide). The final amount is indicated on the shipping vial.
Storage 4 °C,-20 °C,-80 °C
Storage Comment -20°C
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