USP5 antibody (Ubiquitin Specific Peptidase 5)

Details for Product anti-USP5 Antibody No. ABIN6297889
Antigen
  • ISOT
  • AA407472
  • ISOT-1
  • Ucht
  • ubiquitin specific peptidase 5
  • ubiquitin carboxyl-terminal hydrolase 5
  • ubiquitin carboxyl-terminal hydrolase 5, putative
  • ubiquitin specific protease 5
  • ubiquitin specific peptidase 5 (isopeptidase T)
  • USP5
  • CNH02890
  • EHI_049940
  • CC1G_12961
  • MCYG_01862
  • CGB_L3600C
  • PY00546
  • Usp5
Reactivity
Human, Mouse (Murine), Rat (Rattus)
83
19
18
8
7
1
1
1
1
1
Host
Mouse
58
25
2
Clonality
Monoclonal
Conjugate
This USP5 antibody is un-conjugated
4
3
3
2
2
2
1
1
1
1
1
1
Application
67
39
27
9
6
4
1
1
Options
Purpose Mouse Anti-USP5 Antibody
Immunogen This USP5 antibody is generated from a mouse immunized with a recombination protein from the human region of human USP5.
Plasmids, Primers & others Plasmids, Primers & others USP5 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name USP5 (USP5 Antibody Abstract)
Background

Target Description: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored 'Lys-48'-linked polyubiquitin disassembly. Binds linear and 'Lys- 63'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

Gene Symbol: USP5
Gene ID 8078
UniProt P45974
Restrictions For Research Use only
Storage 4 °C,-20 °C
Storage Comment 2-8°C (short-term), -20°C (long-term)
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