Neurofilament, Heavy Polypeptide (NEFH) antibody

Details for Product No. ABIN6297897
Antigen
  • NF-H
  • NF200
  • Nfh
  • mKIAA0845
  • NFH
  • NEFH
  • neurofilament heavy polypeptide
  • neurofilament, heavy polypeptide
  • neurofilament heavy
  • MCYG_06231
  • Nefh
  • NEFH
Reactivity
Chicken, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)
266
200
180
123
121
61
23
23
19
18
18
16
13
9
9
7
3
2
2
1
1
Host
Mouse
215
97
21
Clonality
Monoclonal
Conjugate
Un-conjugated
6
6
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Application
Immunohistochemistry (IHC)
189
143
88
81
62
55
45
43
32
14
14
10
7
6
2
2
2
1
1
Options
Purpose Mouse anti-Human/Mouse/Rat/Chicken/Pig Neurofilament Antibody Cocktail [IHC only]
Immunogen Triton-X 100 insoluble proteins of rat brain (RT-97) and Neurofilaments from porcine spinal cord (NR-4) were used as the immunogen for the Neurofilament antibody cocktail.
Specificity Cytoplasmic
Purification Triton-X 100 insoluble proteins of rat brain (RT-97) and Neurofilaments from porcine spinal cord (NR-4) were used as the immunogen for the Neurofilament antibody cocktail.
Antigen
Alternative Name Neurofilament heavy polypeptide (NEFH Antibody Abstract)
Background

Target Description: This mAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H & NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and cell carcinomas of the lung also express neurofilament.

Gene Symbol: NEFH///KIAA0845///NFH

Gene ID 4744
UniProt P12036
Application Notes Prediluted format : incubate for 30 min at RT (2)
Restrictions For Research Use only
Buffer Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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