Ube2t antibody (Ubiquitin-Conjugating Enzyme E2T (Putative))

Details for Product anti-Ube2t Antibody No. ABIN6298352
Target
Reactivity
Human, Mouse
54
14
3
1
1
1
1
1
1
1
Host
Rabbit
42
7
5
Clonality
Polyclonal
Conjugate
This Ube2t antibody is un-conjugated
5
4
4
3
3
3
1
1
1
1
1
1
Application
46
36
7
4
3
1
1
1
1
Options
Purpose Rabbit Anti-UBE2T Antibody,
Target
Alternative Name UBE2T (Ube2t Antibody Abstract)
Background

Target Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair: acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination.

Gene Symbol: UBE2T

Gene ID 29089
UniProt Q9NPD8
Pathways Chromatin Binding
Restrictions For Research Use only
Storage 4 °C,-20 °C
Storage Comment 2-8°C (short-term), -20°C (long-term)