Glucose-6-Phosphate Dehydrogenase antibody (Middle Region)

Catalog No. ABIN631813

This Rabbit Polyclonal antibody specifically detects Glucose-6-Phosphate Dehydrogenase in WB. It exhibits reactivity toward Human.

Quick Overview for Glucose-6-Phosphate Dehydrogenase antibody (Middle Region) (ABIN631813)

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glucose-6-Phosphate Dehydrogenase antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Glucose-6-Phosphate Dehydrogenase Antibody

Binding Specificity: Middle Region

Specificity: G6 PD antibody was raised against the middle region of G6 D

Purification: Affinity purified

Immunogen: G6 PD antibody was raised using the middle region of G6 D corresponding to a region with amino acids VTKNIHESCMSQIGWNRIIVEKPFGRDLQSSDRLSNHISSLFREDQIYRI

Application Details

Application Notes: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

G6PD Blocking Peptide, (ABIN5613685), is also available for use as a blocking control in assays to test for specificity of this G6PD antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of G0 D antibody in PBS

Concentration: Lot specific

Buffer: PBS

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Target Details for Glucose-6-Phosphate Dehydrogenase

Target: Glucose-6-Phosphate Dehydrogenase (G6PD)

Alternative Name: G6PD

Background: G6PD is a glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia.

Molecular Weight: 57 kDa (MW of target protein)

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones