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GRP94 antibody (AA 460-487)

HSP90B1 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB31597 unconjugated
Catalog No. ABIN655868
  • Target See all GRP94 (HSP90B1) Antibodies
    GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
    Binding Specificity
    • 17
    • 16
    • 16
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 460-487
    Reactivity
    • 126
    • 92
    • 57
    • 38
    • 33
    • 29
    • 28
    • 28
    • 26
    • 26
    • 25
    • 24
    • 24
    • 15
    • 10
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 91
    • 38
    • 20
    • 2
    • 1
    Rabbit
    Clonality
    • 92
    • 60
    Polyclonal
    Conjugate
    • 65
    • 10
    • 9
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GRP94 antibody is un-conjugated
    Application
    • 133
    • 74
    • 62
    • 54
    • 43
    • 37
    • 33
    • 16
    • 13
    • 13
    • 13
    • 11
    • 4
    • 4
    • 2
    • 2
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Predicted Reactivity
    Pr
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This HSP90B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 460-487 amino acids from the Central region of human HSP90B1.
    Clone
    RB31597
    Isotype
    Ig Fraction
    Top Product
    Discover our top product HSP90B1 Primary Antibody
  • Application Notes
    WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Target
    GRP94 (HSP90B1) (Heat Shock Protein 90kDa beta (Grp94), Member 1 (HSP90B1))
    Alternative Name
    HSP90B1 (HSP90B1 Products)
    Background
    HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 is an endoplasmic reticulum HSP90 protein. Other HSP90 proteins are found in cytosol (see HSP90AA1, MIM 140571) and mitochondria (TRAP1, MIM 606219) (Chen et al., 2005 [PubMed 16269234]).
    Molecular Weight
    92469
    Gene ID
    7184
    NCBI Accession
    NP_003290
    UniProt
    P14625
    Pathways
    Thyroid Hormone Synthesis, Activation of Innate immune Response, ER-Nucleus Signaling, Toll-Like Receptors Cascades
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