CD164 Molecule, Sialomucin (CD164) antibody

Details for Product No. ABIN6559813
Antigen
Reactivity
Human
37
15
14
Host
Mouse
28
12
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
3
2
2
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blotting (WB)
19
19
12
12
5
3
2
Options
Immunogen Breast tumor cell line T-47D
Clone 67D2
Isotype IgG1
Specificity The mouse monoclonal antibody 67D2 recognizes class III epitope (not sensitive to sialidase, N-glycanase, O-glycosidase, and O-sialoglycoprotease) of CD164, a sialomucin expressed in hematopoietic myeloid and erythroid progenitors, activated basophils, and in various carcinomas and leukemic cells.
HLDA 8
Cross-Reactivity (Details) Human
Purification Purified from hybridoma culture supernatant by protein-A affinity chromatography.
Purity > 95 % (by SDS-PAGE)
Antigen
Alternative Name CD164 (CD164 Antibody Abstract)
Background CD164, also known as endolyn, is a type I transmembrane protein with heavily glycosylated extracellular part containing sialic acid and glycosaminoglycan residues. CD164 plays both adhesive and antiadhesive role and serves as a potent negative regulator for CD34+ CD38- hematopoietic progenitor cell proliferation. It has also been reported to be involved in myogenic differentiation and cancer metastasis. The adhesive and negative regulatory functions seem to depend on different posttranslational modifications of CD164 protein.
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C