Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) antibody

Details for Product No. ABIN6566468
Antigen
Reactivity
Human, Rat (Rattus)
261
196
174
16
8
3
3
3
2
2
2
2
1
1
1
Host
Rabbit
249
69
Clonality
Polyclonal
Conjugate
Un-conjugated
15
10
8
8
8
8
8
8
7
7
7
6
3
3
3
3
3
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
232
115
96
50
40
29
26
21
8
4
4
3
2
2
2
Options
Immunogen Recombinant protein of human PIK3R1
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name PI 3 kinase p85 alpha (PI3K p85a Antibody Abstract)
Background

Synonyms: GRB1,p85 alpha,p85,P85A,Phosphatidylinositol 3 kinase associated p 85 alpha,Phosphatidylinositol 3 kinase regulatory 1,Phosphatidylinositol 3 kinase,regulatory subunit,polypeptide 1 (p85 alpha),Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,Phosphatidylinositol 3-kinase regulatory subunit alpha,Phosphoinositide 3 kinase,regulatory subunit 1 (alpha),PI3 kinase p85 subunit alpha,PI3-kinase regulatory subunit alpha,PI3-kinase subunit p85-alpha,PI3K,PI3K regulatory subunit alpha,Pik3r1,PtdIns 3 kinase p85 alpha,PtdIns-3-kinase regulatory subunit alpha,PtdIns-3-kinase regulatory subunit p85-alpha

Background: Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms.

Molecular Weight

Observed_MW: 90kDa

Calculated_MW: 42kDa/49kDa/53kDa/83kDa/84kDa

Gene ID 5295
UniProt P27986
Pathways TCR Signaling, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) antibody (ABIN6566468) Western blot analysis of extracts of THP-1 cells, using PIK3R1 antibody.
Image no. 2 for anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) antibody (ABIN6566468) Immunohistochemistry of paraffin-embedded rat brain using PIK3R1 antibody.