Non-Muscle Myosin Heavy Polypeptide 9 (MYH9) antibody

Details for Product No. ABIN6566485
Antigen
Reactivity
Human, Mouse (Murine)
121
32
30
5
4
3
3
1
1
Host
Rabbit
99
20
2
1
1
1
Clonality
Polyclonal
Conjugate
Un-conjugated
10
8
8
4
4
4
2
2
2
2
2
2
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
90
81
32
26
17
16
6
4
3
2
2
2
1
Options
Immunogen Recombinant protein of human MYH9
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name MYH9 (MYH9 Antibody Abstract)
Background

Synonyms: BDPLT 6,BDPLT6,Cellular myosin heavy chain,Cellular myosin heavy chain type A,DFNA 17,DFNA17,EPSTS,FTNS,MGC104539,MHA,MYH 2A,MYH 9,MYH2A,MYH9,MYH9,MYHas8,MyHC 2A,MyHC IIa,MyHC2A,MyHCIIa,MYHSA 2,MYHSA2,Myosin 9,Myosin heavy chain 9,Myosin heavy chain 9 non muscle,Myosin heavy chain,Myosin heavy chain non muscle IIa,Myosin heavy chain nonmuscle IIa,Myosin heavy polypeptide 2,Myosin heavy polypeptide 9 non muscle,Myosin-9,Myosin9,NMHC II A,NMMHC A,NMMHC II a,NMMHC II-a,NMMHC IIA,NMMHC-A,NMMHC-IIA,NMMHCA,Non muscle myosin heavy chain A,Non muscle myosin heavy chain,Non muscle myosin heavy chain II A,Non muscle myosin heavy polypeptide 9,non-muscle IIa,Non-muscle myosin heavy chain A,Non-muscle myosin heavy chain IIa,Nonmuscle myosin heavy chain A,Nonmuscle myosin heavy chain II A,type A

Background: This gene encodes a conventional non-muscle myosin, this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.

Molecular Weight

Observed_MW: 250kDa

Calculated_MW: 159kDa/226kDa

Gene ID 4627
UniProt P35579
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling, Integrin Complex
Application Notes WB 1:1000 - 1:2000 IHC 1:50 - 1:100
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Non-Muscle Myosin Heavy Polypeptide 9 (MYH9) antibody (ABIN6566485) Immunohistochemistry of paraffin-embedded human esophagus using MYH9 antibody.
Image no. 2 for anti-Non-Muscle Myosin Heavy Polypeptide 9 (MYH9) antibody (ABIN6566485) Western blot analysis of extracts of various cell lines, using MYH9 antibody.
Image no. 3 for anti-Non-Muscle Myosin Heavy Polypeptide 9 (MYH9) antibody (ABIN6566485) Immunohistochemistry of paraffin-embedded human stomach using MYH9 antibody.