Myosin 9 antibody (AA 1711-1960)
Quick Overview for Myosin 9 antibody (AA 1711-1960) (ABIN1513234)
Target
See all Myosin 9 (MYH9) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1711-1960
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Sequence
- ANSSGKGALA LEEKRRLEAR IAQLEEELEE EQGNTELIND RLKKANLQID QINTDLNLER SHAQKNENAR QQLERQNKEL KVKLQEMEGT VKSKYKASIT ALEAKIAQLE EQLDNETKER QAACKQVRRT EKKLKDVLLQ VDDERRNAEQ YKDQADKAST RLKQLKRQLE EAEEEAQRAN ASRRKLQREL EDATETADAM NREVSSLKNK LRRGDLPFVV PRRMARKGAG DGSDEEVDGK ADGAEAKPAE
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Cross-Reactivity
- Human, Mouse, Rat
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Characteristics
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1711-1960 of human MYH9 (NP_002464.1).
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Isotype
- IgG
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Application Notes
- WB,1:1000 - 1:2000,IHC,1:50 - 1:100,IP,1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid freeze / thaw cycles
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Storage
- -20 °C
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Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Myosin 9 (MYH9)
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Alternative Name
- MYH9
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Background
- This gene encodes a conventional non-muscle myosin, this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.,MYH9,BDPLT6,DFNA17,EPSTS,FTNS,MHA,NMHC-II-A,NMMHC-IIA,NMMHCA,myosin-9,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,MYH9
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Molecular Weight
- 159 kDa/226 kDa
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Gene ID
- 4627
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UniProt
- P35579
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Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Integrin Complex
Target
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