ATG5 antibody (ATG5 Autophagy Related 5 Homolog (S. Cerevisiae))

Details for Product anti-ATG5 Antibody No. ABIN6566496
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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2
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1
Host
Rabbit
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2
Clonality
Polyclonal
Conjugate
This ATG5 antibody is un-conjugated
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Application
Immunohistochemistry (IHC), Western Blotting (WB)
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Options
Immunogen Recombinant protein of human ATG5
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name ATG5 (ATG5 Antibody Abstract)
Background

Synonyms: APG 5,APG 5L,APG5,APG5 autophagy 5 like,APG5 like,APG5-like,APG5L,Apoptosis specific protein,Apoptosis-specific protein,ASP,ATG 5,Atg5,ATG5 autophagy related 5 homolog,ATG5,Autophagy protein 5,Autophagy related 5,hAPG5,Homolog of S Cerevisiae autophagy 5,OTTHUMP00000040507

Background: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.
Molecular Weight

Observed_MW: 58kDa

Calculated_MW: 22kDa/32kDa
Gene ID 9474
UniProt Q9H1Y0
Pathways Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Autophagy
Application Notes WB 1:500 - 1:2000 IHC 1:50 - 1:100
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-ATG5 Autophagy Related 5 Homolog (S. Cerevisiae) (ATG5) antibody (ABIN6566496) Western blot analysis of extracts of various cell lines, using ATG5 antibody.
Image no. 2 for anti-ATG5 Autophagy Related 5 Homolog (S. Cerevisiae) (ATG5) antibody (ABIN6566496) Immunohistochemistry of paraffin-embedded human prostate using ATG5 antibody.