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FASL antibody

FASL Reactivity: Human, Mouse, Rat WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6566520
  • Target See all FASL Antibodies
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    Reactivity
    • 98
    • 47
    • 34
    • 18
    • 6
    • 5
    • 3
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 69
    • 28
    • 10
    • 5
    • 4
    • 1
    Rabbit
    Clonality
    • 76
    • 41
    Polyclonal
    Conjugate
    • 67
    • 12
    • 10
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FASL antibody is un-conjugated
    Application
    • 79
    • 53
    • 26
    • 23
    • 21
    • 17
    • 13
    • 13
    • 11
    • 7
    • 5
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Purification
    Affinity purification
    Immunogen
    A synthetic peptide of human FASLG
    Isotype
    IgG
    Top Product
    Discover our top product FASL Primary Antibody
  • Application Notes
    WB 1:500 - 1:2000
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    FASL (Fas Ligand (TNF Superfamily, Member 6) (FASL))
    Alternative Name
    FASLG (FASL Products)
    Synonyms
    ALPS1B antibody, APT1LG1 antibody, APTL antibody, CD178 antibody, CD95-L antibody, CD95L antibody, FASL antibody, TNFSF6 antibody, fasl antibody, Fas-L antibody, Faslg antibody, Tnfsf6 antibody, gld antibody, Apt1Lg1 antibody, Fasl antibody, FASLG antibody, zgc:162027 antibody, Fas ligand antibody, Fas ligand L homeolog antibody, Fas ligand (TNF superfamily, member 6) antibody, FASLG antibody, faslg.L antibody, Fasl antibody, Faslg antibody, faslg antibody
    Background

    Synonyms: ALPS1B,Apoptosis (APO 1) antigen ligand 1,Apoptosis antigen ligand 1,Apoptosis antigen ligand,APT1LG1,APTL,CD178,CD178 antigen,CD95 ligand,CD95-L,CD95L,CD95L protein,Fas antigen ligand,Fas L,Fas ligand (TNF superfamily member 6),Fas ligand,FASL,Fasl Fas ligand (TNF superfamily member 6),FASLG,Generalized lymphoproliferative disease,Gld,soluble form,TNFL6,TNFSF6,Tumor necrosis factor (ligand) superfamily member 6,Tumor necrosis factor ligand superfamily member 6

    Background: This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.

    Molecular Weight

    Observed_MW: 45kDa

    Calculated_MW: 14kDa/31kDa

    Gene ID
    356
    UniProt
    P48023
    Pathways
    Apoptosis, EGFR Signaling Pathway, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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