IRF4 antibody (Interferon Regulatory Factor 4)

Details for Product anti-IRF4 Antibody No. ABIN6566604
Antigen
Reactivity
Mouse (Murine), Rat (Rattus)
131
62
38
5
5
5
4
4
4
3
2
2
2
2
1
Host
Rabbit
100
22
9
2
2
Clonality
Polyclonal
Conjugate
This IRF4 antibody is un-conjugated
4
3
3
3
3
3
3
1
1
1
1
1
Application
Western Blotting (WB)
113
61
40
21
20
11
9
5
4
3
3
2
1
1
Options
Immunogen Recombinant protein of human IRF4
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name IRF4 (IRF4 Antibody Abstract)
Background

Synonyms: Interferon regulatory factor 4,IRF 4,IRF-4,Irf4,IRF4,LSIRF,Lymphocyte specific interferon regulatory factor,Lymphocyte specific IRF,Lymphocyte-specific interferon regulatory factor,Multiple myeloma oncogene 1,MUM 1,MUM1,NF EM5,NF-EM5,NFEM5,PU.1 interaction partner,Sfpi1/PU.1 interaction partner,Transcriptional activator PIP

Background: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6,14)(p25,q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight

Observed_MW: 52kDa

Calculated_MW: 51kDa

Gene ID 3662
UniProt Q15306
Pathways Chromatin Binding
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Interferon Regulatory Factor 4 (IRF4) antibody (ABIN6566604) Western blot analysis of extracts of various cell lines, using IRF4 antibody.