FGF1 antibody

Catalog No. ABIN6566640

Product Details anti-FGF1 Antibody

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogen: Recombinant protein of human FGF1

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000 IHC 1:100 - 1:200

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for FGF1

Target: FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

Alternative Name: FGF1 (FGF1 Products)

Background:

Synonyms: Acidic fibroblast growth factor,aFGF,Beta endothelial cell growth factor,Beta-endothelial cell growth factor,ECGF,ECGF beta,ECGF-beta,ECGFA,ECGFB,Endothelial Cell Growth Factor alpha,Endothelial Cell Growth Factor beta,FGF 1,FGF alpha,Fgf1,FGF1,FGFA,Fibroblast Growth Factor 1 Acidic,Fibroblast growth factor 1,GLIO703,HBGF 1,HBGF-1,HBGF1,Heparin binding growth factor 1,Heparin binding growth factor 1 precursor,Heparin-binding growth factor 1

Background: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described.

Molecular Weight:

Observed_MW: 17kDa

Calculated_MW: 6kDa/17kDa

Gene ID: 2246

UniProt: P05230

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway