Synonyms: Villin 2 ezrin,CVIL,CVL,Cytovillin 2,Cytovillin,DKFZp762H157,Epididymis secretory protein Li 105,EZR,EZRI,Ezrin,FLJ26216,HEL S 105,MGC1584,p81,VIL 2,VIL2,Villin 2 (ezrin),Villin 2,Villin-2,Villin2
Background: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.