Synonyms: AGP/EBP,C EBP beta,C/EBP beta,C/EBP related protein 2,CCAAT Enhancer Binding Protein beta,CCAAT/enhancer-binding protein beta,CEBPB,CEBPB,CRP2,IL 6DBP,IL6DBP,Interleukin 6 dependent binding protein,LAP,Liver activator protein,Liver enriched transcriptional activator,NF IL6,NFIL6,Nuclear factor NF IL6,Nuclear factor NF-IL6,SF B,SFB,Silencer factor B,TCF-5,TCF5,Transcription factor 5
Background: This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions.