CD53 antibody (CD53)

Details for Product anti-CD53 Antibody No. ABIN6566768
Antigen
Reactivity
Human, Mouse (Murine)
172
12
9
6
2
Host
Rabbit
148
32
1
Clonality
Polyclonal
Conjugate
This CD53 antibody is un-conjugated
25
19
11
5
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
147
49
49
43
28
21
16
13
12
7
4
3
2
Options
Immunogen Recombinant protein of human CD53
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name CD53 (CD53 Antibody Abstract)
Background

Synonyms: AI323659,Antigen MOX44 identified by monoclonal MRC-OX44,CD 53,CD53,CD53 antigen,CD53 antigen,isoform CRA_b,CD53 glycoprotein,Cd53 Molecule,CD53 tetraspan antigen,CD53,Cell surface glycoprotein CD53,Leukocyte antigen MRC OX-44,Leukocyte surface antigen CD53,MOX 44,MOX44,OTTHUMP00000059505,Ox-44,OX44,RATOX44,Tetraspanin 25,Tetraspanin-25,Tetraspanin25,Transmembrane glycoprotein,TSPAN 25,Tspan-25,TSPAN25

Background: The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants.

Molecular Weight

Observed_MW: 35kDa

Calculated_MW: 24kDa

Gene ID 963
UniProt P19397
Application Notes WB 1:1000 - 1:4000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-CD53 (CD53) antibody (ABIN6566768) Western blot analysis of extracts of various cell lines, using CD53 antibody.