TXNL4A antibody

Catalog No. ABIN6566788

Product Details anti-TXNL4A Antibody

Target: TXNL4A (Thioredoxin-Like 4A (TXNL4A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TXNL4A antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human TXNL4A

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for TXNL4A

Target: TXNL4A (Thioredoxin-Like 4A (TXNL4A))

Alternative Name: TXNL4A (TXNL4A Products)

Background:

Synonyms: BMKS,DIB 1,DIB1,DIM 1,DIM1,DIM1 protein homolog,HsT161,SNRNP15,Spliceosomal U5 snRNP specific 15 kDa protein,Spliceosomal U5 snRNP-specific 15 kDa protein,Thioredoxin like 4,Thioredoxin like 4A,Thioredoxin like protein 4A,Thioredoxin like U5 snRNP protein U5 15kD,Thioredoxin-like protein 4A,Thioredoxin-like U5 snRNP protein U5-15kD,TXN4A,TXNL 4,TXNL 4A,TXNL4,txnl4a,U5 15kD

Background: The protein encoded by this gene is a member of the U5 small ribonucleoprotein particle (snRNP), and is involved in pre-mRNA splicing. This protein contains a thioredoxin-like fold and it is expected to interact with multiple proteins. Protein-protein interactions have been observed with the polyglutamine tract-binding protein 1 (PQBP1). Mutations in both the coding region and promoter region of this gene have been associated with Burn-McKeown syndrome, which is a rare disorder characterized by craniofacial dysmorphisms, cardiac defects, hearing loss, and bilateral choanal atresia. A pseudogene of this gene is found on chromosome 2. Alternative splicing results in multiple transcript variants.

Molecular Weight:

Observed_MW: 13kDa

Calculated_MW: 16kDa

Gene ID: 10907

UniProt: P83876

Pathways: Ribonucleoprotein Complex Subunit Organization