CRLF2 antibody
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- Target See all CRLF2 Antibodies
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CRLF2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purification
- Affinity purification
- Immunogen
- Recombinant protein of human CRLF2
- Isotype
- IgG
- Top Product
- Discover our top product CRLF2 Primary Antibody
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- Application Notes
- WB 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- Alternative Name
- CRLF2 (CRLF2 Products)
- Synonyms
- CRLF2 antibody, CRL2 antibody, CRLF2Y antibody, TSLPR antibody, CRLM2 antibody, Ly114 antibody, Tpte2 antibody, Tslpr antibody, Crl2 antibody, cytokine receptor like factor 2 antibody, cytokine receptor-like factor 2 antibody, CRLF2 antibody, Crlf2 antibody
- Background
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Synonyms: CRL 2,CRL2,CRLF 2,Crlf2,CRLF2,CRLF2Y,Cytokine receptor CRL2 precusor,Cytokine receptor like 2,Cytokine receptor like factor 2,Cytokine receptor like factor 2 precursor,Cytokine receptor-like 2,Cytokine receptor-like factor 2,IL XR,IL-XR,ILXR,Thymic stromal derived lymphopoietin receptor,Thymic stromal lymphopoietin protein receptor,Thymic stromal lymphopoietin receptor,TSLP receptor,TSLPR
Background: This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.
- Molecular Weight
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Observed_MW: 50kDa
Calculated_MW: 26kDa/29kDa/42kDa
- Gene ID
- 64109
- UniProt
- Q9HC73
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