CRLF2 antibody (Cytokine Receptor-Like Factor 2)

Details for Product anti-CRLF2 Antibody No. ABIN6566796
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
71
30
19
Host
Rabbit
74
19
3
Clonality
Polyclonal
Conjugate
This CRLF2 antibody is un-conjugated
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
Application
Western Blotting (WB)
53
29
26
17
15
8
6
2
2
1
Options
Immunogen Recombinant protein of human CRLF2
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name CRLF2 (CRLF2 Antibody Abstract)
Background

Synonyms: CRL 2,CRL2,CRLF 2,Crlf2,CRLF2,CRLF2Y,Cytokine receptor CRL2 precusor,Cytokine receptor like 2,Cytokine receptor like factor 2,Cytokine receptor like factor 2 precursor,Cytokine receptor-like 2,Cytokine receptor-like factor 2,IL XR,IL-XR,ILXR,Thymic stromal derived lymphopoietin receptor,Thymic stromal lymphopoietin protein receptor,Thymic stromal lymphopoietin receptor,TSLP receptor,TSLPR

Background: This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.

Molecular Weight

Observed_MW: 50kDa

Calculated_MW: 26kDa/29kDa/42kDa

Gene ID 64109
UniProt Q9HC73
Application Notes WB 1:200 - 1:1000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Cytokine Receptor-Like Factor 2 (CRLF2) antibody (ABIN6566796) Western blot analysis of extracts of various cell lines, using CRLF2 antibody.