ADA antibody (Adenosine Deaminase)

Details for Product anti-ADA Antibody No. ABIN6566804
Antigen
Reactivity
Human, Mouse (Murine)
122
46
41
27
4
4
3
2
2
2
2
1
Host
Rabbit
117
32
1
Clonality
Polyclonal
Conjugate
This ADA antibody is un-conjugated
14
9
6
4
4
4
2
2
2
2
2
2
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
121
79
25
19
17
14
13
10
5
3
2
2
2
2
1
1
1
Options
Immunogen Recombinant protein of human ADA
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name ADA (ADA Antibody Abstract)
Background

Synonyms: Adenosine Deaminase,EC 3.5.4.4,Adenosine Aminohydrolase,ADA1.

Background: This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.

Molecular Weight

Observed_MW: 43kDa

Calculated_MW: 40kDa

Gene ID 100
UniProt P00813
Pathways Regulation of G-Protein Coupled Receptor Protein Signaling, Ribonucleoside Biosynthetic Process
Application Notes WB 1:500 - 1:2000 IF 1:50 - 1:200
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Adenosine Deaminase (ADA) antibody (ABIN6566804) Immunofluorescence analysis of U2OS cells using ADA antibody.
Image no. 2 for anti-Adenosine Deaminase (ADA) antibody (ABIN6566804) Western blot analysis of extracts of various cell lines, using ADA antibody.