Synonyms: Choline phosphatase 2,EC 22.214.171.124 ,hPLD 2,hPLD2,mPLD2,Phosphatidylcholine hydrolyzing phospholipase D2,Phosphatidylcholine-hydrolyzing phospholipase D2,Phospholipase D2,PhospholipaseD2,PLD 2,PLD1C,Pld2,PLD2,Pldc,rPLD2
Background: The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.