Phospholipase D2 antibody

Catalog No. ABIN6566807

Product Details anti-Phospholipase D2 Antibody

Target: Phospholipase D2 (PLD2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Phospholipase D2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogen: Recombinant protein of human PLD2

Isotype: IgG

Application Details

Application Notes: WB 1:1000 - 1:3000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Phospholipase D2

Target: Phospholipase D2 (PLD2)

Alternative Name: PLD2 (PLD2 Products)

Synonyms: Pldc antibody, PLD2 antibody, phospholipase D2 antibody, PLD2 antibody, Pld2 antibody, pld2 antibody, CpipJ_CPIJ013122 antibody, VDBG_00892 antibody

Background:

Synonyms: Choline phosphatase 2,EC 3.1.4.4 ,hPLD 2,hPLD2,mPLD2,Phosphatidylcholine hydrolyzing phospholipase D2,Phosphatidylcholine-hydrolyzing phospholipase D2,Phospholipase D2,PhospholipaseD2,PLD 2,PLD1C,Pld2,PLD2,Pldc,rPLD2

Background: The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 110kDa

Calculated_MW: 38kDa/104kDa/105kDa

Gene ID: 5338

UniProt: O14939

Pathways: RTK Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling