Histone H3.3 antibody

Details for Product No. ABIN6566819
Antigen
Reactivity
Human
86
25
20
3
3
2
2
2
2
1
1
1
1
1
1
Host
Rabbit
84
6
Clonality
Polyclonal
Conjugate
Un-conjugated
9
8
8
1
1
1
1
1
1
Application
Western Blotting (WB)
62
54
23
20
13
10
10
6
2
1
1
1
1
1
Options
Immunogen Recombinant protein of human H3F3B
Isotype IgG
Purification Affinity purification
Antigen
Background

Synonyms: H3 histone family 3A,H3 histone family 3B,H3 histone,family 3B (H3.3B),H3.3,H3.3A,H3.3B,H33,H3F3,H3F3A,H3f3b,Histone H3.3,Histone H3.3Q,Histone H3.A,Histone H3.B,MGC87782,MGC87783

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded by this gene is a replication-independent histone that is a member of the histone H3 family. Pseudogenes of this gene have been identified on the X chromosome, and on chromosomes 5, 13 and 17.

Molecular Weight

Observed_MW: 15kDa

Calculated_MW: 15kDa

Gene ID 3020
UniProt P84243
Application Notes WB 1:500 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-Histone H3.3 antibody (ABIN6566819) Western blot analysis of extracts of various cell lines, using H3F3B antibody.