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Synonyms: 14 3 3 alpha,14 3 3 protein beta/alpha,14-3-3 protein beta/alpha,1433B,Brain protein 14 3 3 beta isoform,GW128,HS 1,KCIP-1,KCIP1,N-terminally processed,Protein 1054,Protein kinase C inhibitor protein 1,YWHAA,YWHAB
Background: This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.