eIF2Bgamma antibody

Details for Product No. ABIN6566842
Antigen
Reactivity
Human, Mouse (Murine), Rat (Rattus)
3
3
Host
Rabbit
3
Clonality
Polyclonal
Application
Western Blotting (WB)
3
3
Options
Immunogen Recombinant protein of human EIF2B3
Isotype IgG
Purification Affinity purification
Antigen
Alternative Name EIF2B gamma
Background

Synonyms: EI2BG,EIF 2B,eIF 2B GDP GTP exchange factor subunit gamma,eIF-2B GDP-GTP exchange factor subunit gamma,eIF2B-gamma,Eif2b3,EIF2Bgamma,Eukaryotic translation initiation factor 2B subunit 3 gamma,Eukaryotic translation initiation factor 2B,gamma,eukaryotic translation initiation factor 2B,subunit 3 gamma,58  kDa,OTTHUMP00000010262,OTTHUMP00000010263,Translation initiation factor eIF-2B subunit gamma

Background: The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight

Observed_MW: 50kDa

Calculated_MW: 44kDa/46kDa/50kDa

Gene ID 8891
UniProt Q9NR50
Application Notes WB 1:1000 - 1:2000
Restrictions For Research Use only
Concentration 1 mg/mL
Buffer Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze / thaw cycles.
Supplier Images
Image no. 1 for anti-eIF2Bgamma antibody (ABIN6566842) Western blot analysis of extracts of various cell lines, using EIF2B3 antibody.